WWW.MASH.DOBROTA.BIZ
    -
 

.., .. ...

612.017.1:591.441:616-092.9

.., . .

, ,

180 - ( , ) , , . . .

: , , , .

1 - , , - 1 7 15 30 60 [1, 9] .



, - 6 6 6 6 6 30 , 6 6 6 6 6 30 , , 6 6 6 6 6 30 , - 6 6 6 6 6 30 6 6 6 6 6 30

   

. 15, 30 60 10,17% (1 ), 12,75% (7 ) 8,80% (15 ) , - (. 7). . 10,50% 8,75% 30 (. 5). 60 , . - - . , , - , 1, 7, 15 , . , - 7,43%, 6,81%, 5,31% 18,17%, 12,73%, 10,15%, . . .

   

FEATURES OF HISTOLOGICAL STRUCTURE IN THE WHITE PULP OF RAT SPLEEN



DURING DIFFERENT PERIODS OF POSTNATAL ONTOGENESIS UNDER EXPERIMENTAL

IMMUNOSUPPRESSION

Kashchenko S.A., Bobrysheva I.V .

State Establishment Lugansk State Medical University, Lugansk, Ukraine During the experiment, conducted on 180 white outbred male rats of three age periods (pubertal, reproductive and of expressed age-related changes) with the use of histological and morphometric methods, followed by statistical analysis, it was established that experimentally simulated immunosuppressive condition caused morphological remodeling in the animal spleen, which was manifested as white pulp hypoplasia. The highest level of spleen reactivity in response to a cytostatic agent was observed in pubertal animals. Changes in the spleen white pulp of rats with expressed age-related changes took place against the background of involutive processes .

Key words: rats, spleen, white pulp, yclophosphamide .

   






:

? .. " " .. ...

. Bock, Emil: Das Evangelium: Betrachtungen zum Neuen Testament / Emil Bock. [Die Hrsg. besorgte Gundhild Kaer-Bock]. Stuttgart :...

1. / .. , .. - // .: ; , 2007, 234 . .. - ...

1 XI , ...

, , . 3 (75) 2017 ISSN 2304-334-02 10-30%- . 1:2000; 1:5000 1:10000 , 1:500; 1:200 . , ...

.. , .. , 2013 616.124.2:616.127-007 .. , .. ...

"- " ...

.., .. ) ^0P i %.ru / ib r-l I he us V ak .. , . . .ru ib r-l he us ak ...




 
<<     |    
2019 www.mash.dobrota.biz - -

, .
, , , , 1-2 .